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Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription

BACKGROUND: LMP-420 is a boronic acid-containing purine nucleoside analogue that transcriptionally inhibits TNF production but is non-cytotoxic to TNF-producing cells. METHODS: This study investigated the efficacy of LMP-420 as an anti-inflammatory agent in acute and chronic colitis induced by oral...

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Detalles Bibliográficos
Autores principales: Hale, Laura P, Cianciolo, George
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2322983/
https://www.ncbi.nlm.nih.gov/pubmed/18331642
http://dx.doi.org/10.1186/1476-9255-5-4

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