Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin

BACKGROUND: Repulsive guidance molecule c (RGMc or hemojuvelin), a glycosylphosphatidylinositol-linked glycoprotein expressed in liver and striated muscle, plays a central role in systemic iron balance. Inactivating mutations in the RGMc gene cause juvenile hemochromatosis (JH), a rapidly progressin...

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Detalles Bibliográficos
Autores principales: Kuninger, David, Kuns-Hashimoto, Robin, Nili, Mahta, Rotwein, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323002/
https://www.ncbi.nlm.nih.gov/pubmed/18384687
http://dx.doi.org/10.1186/1471-2091-9-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323002/
https://www.ncbi.nlm.nih.gov/pubmed/18384687
http://dx.doi.org/10.1186/1471-2091-9-9

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