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Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin
BACKGROUND: Repulsive guidance molecule c (RGMc or hemojuvelin), a glycosylphosphatidylinositol-linked glycoprotein expressed in liver and striated muscle, plays a central role in systemic iron balance. Inactivating mutations in the RGMc gene cause juvenile hemochromatosis (JH), a rapidly progressin...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323002/ https://www.ncbi.nlm.nih.gov/pubmed/18384687 http://dx.doi.org/10.1186/1471-2091-9-9 |