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Very mild disease phenotype of congenic Cftr(TgH(neoim)Hgu )cystic fibrosis mice

BACKGROUND: A major boost to cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modifier...

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Detalles Bibliográficos
Autores principales: Tóth, Balázs, Wilke, Martina, Stanke, Frauke, Dorsch, Martina, Jansen, Silke, Wedekind, Dirk, Charizopoulou, Nikoletta, Bot, Alice, Burmester, Marion, Leonhard-Marek, Sabine, de Jonge, Hugo R, Hedrich, Hans-Jürgen, Breves, Gerhard, Tümmler, Burkhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323021/
https://www.ncbi.nlm.nih.gov/pubmed/18400105
http://dx.doi.org/10.1186/1471-2156-9-28