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Very mild disease phenotype of congenic Cftr(TgH(neoim)Hgu )cystic fibrosis mice
BACKGROUND: A major boost to cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modifier...
Autores principales: | Tóth, Balázs, Wilke, Martina, Stanke, Frauke, Dorsch, Martina, Jansen, Silke, Wedekind, Dirk, Charizopoulou, Nikoletta, Bot, Alice, Burmester, Marion, Leonhard-Marek, Sabine, de Jonge, Hugo R, Hedrich, Hans-Jürgen, Breves, Gerhard, Tümmler, Burkhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323021/ https://www.ncbi.nlm.nih.gov/pubmed/18400105 http://dx.doi.org/10.1186/1471-2156-9-28 |
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