Turning up the volume on mutational pressure: Is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3)

APOBEC3G and APOBEC3F are human cytidine deaminases that serve as innate antiviral defense mechanisms primarily by introducing C-to-U changes in the minus strand DNA of retroviruses during replication (resulting in G-to-A mutations in the genomic sense strand sequence). The HIV-1 Vif protein counter...

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Detalles Bibliográficos
Autores principales: Pillai, Satish K, Wong, Joseph K, Barbour, Jason D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323022/
https://www.ncbi.nlm.nih.gov/pubmed/18339206
http://dx.doi.org/10.1186/1742-4690-5-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323022/
https://www.ncbi.nlm.nih.gov/pubmed/18339206
http://dx.doi.org/10.1186/1742-4690-5-26

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