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Changing Selective Pressure during Antigenic Changes in Human Influenza H3

The rapid evolution of influenza viruses presents difficulties in maintaining the optimal efficiency of vaccines. Amino acid substitutions result in antigenic drift, a process whereby antisera raised in response to one virus have reduced effectiveness against future viruses. Interestingly, while ami...

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Detalles Bibliográficos
Autores principales: Blackburne, Benjamin P., Hay, Alan J., Goldstein, Richard A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323114/
https://www.ncbi.nlm.nih.gov/pubmed/18451985
http://dx.doi.org/10.1371/journal.ppat.1000058