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Changing Selective Pressure during Antigenic Changes in Human Influenza H3
The rapid evolution of influenza viruses presents difficulties in maintaining the optimal efficiency of vaccines. Amino acid substitutions result in antigenic drift, a process whereby antisera raised in response to one virus have reduced effectiveness against future viruses. Interestingly, while ami...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323114/ https://www.ncbi.nlm.nih.gov/pubmed/18451985 http://dx.doi.org/10.1371/journal.ppat.1000058 |