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Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells

BACKGROUND: Ambient air pollution is associated with increased cardiovascular morbidity and mortality. We have found that exposure to ambient ultrafine particulate matter, highly enriched in redox cycling organic chemicals, promotes atherosclerosis in mice. We hypothesize that these pro-oxidative ch...

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Detalles Bibliográficos
Autores principales: Gong, Ke Wei, Zhao, Wei, Li, Ning, Barajas, Berenice, Kleinman, Michael, Sioutas, Constantinos, Horvath, Steve, Lusis, Aldons J, Nel, Andre, Araujo, Jesus A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323217/
https://www.ncbi.nlm.nih.gov/pubmed/17655762
http://dx.doi.org/10.1186/gb-2007-8-7-r149