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Accuracy and quality of massively parallel DNA pyrosequencing
BACKGROUND: Massively parallel pyrosequencing systems have increased the efficiency of DNA sequencing, although the published per-base accuracy of a Roche GS20 is only 96%. In genome projects, highly redundant consensus assemblies can compensate for sequencing errors. In contrast, studies of microbi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323236/ https://www.ncbi.nlm.nih.gov/pubmed/17659080 http://dx.doi.org/10.1186/gb-2007-8-7-r143 |