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Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres

BACKGROUND: Mammalian centromere formation is dependent on chromatin that contains centromere protein (CENP)-A, which is the centromere-specific histone H3 variant. Human neocentromeres have acquired CENP-A chromatin epigenetically in ectopic chromosomal locations on low-copy complex DNA. Neocentrom...

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Detalles Bibliográficos
Autores principales: Alonso, Alicia, Fritz, Björn, Hasson, Dan, Abrusan, György, Cheung, Fanny, Yoda, Kinya, Radlwimmer, Bernhard, Ladurner, Andreas G, Warburton, Peter E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323242/
https://www.ncbi.nlm.nih.gov/pubmed/17651496
http://dx.doi.org/10.1186/gb-2007-8-7-r148