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A SAP30 Complex Inhibits IFN-β Expression in Rift Valley Fever Virus Infected Cells
Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon β (IFN-β) gene expression. We demonstrate here that NSs interacts with the host protein SAP30, which belongs to Sin3A/NCoR/HDACs repressor complexes and interacts with the t...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323286/ https://www.ncbi.nlm.nih.gov/pubmed/18225953 http://dx.doi.org/10.1371/journal.ppat.0040013 |