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Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody

Identifying functionally critical regions of the malaria antigen AMA1 (apical membrane antigen 1) is necessary to understand the significance of the polymorphisms within this antigen for vaccine development. The crystal structure of AMA1 in complex with the Fab fragment of inhibitory monoclonal anti...

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Detalles Bibliográficos
Autores principales: Coley, Andrew M, Gupta, Aditi, Murphy, Vince J, Bai, Tao, Kim, Hanna, Anders, Robin F, Foley, Michael, Batchelor, Adrian H
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323298/
https://www.ncbi.nlm.nih.gov/pubmed/17907804
http://dx.doi.org/10.1371/journal.ppat.0030138