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Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein

Hepatitis C virus (HCV) is a positive-strand RNA virus that frequently causes persistent infections and is uniquely associated with the development of hepatocellular carcinoma. While the mechanism(s) by which the virus promotes cancer are poorly defined, previous studies indicate that the HCV RNA-de...

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Detalles Bibliográficos
Autores principales: Munakata, Tsubasa, Liang, Yuqiong, Kim, Seungtaek, McGivern, David R, Huibregtse, Jon, Nomoto, Akio, Lemon, Stanley M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323300/
https://www.ncbi.nlm.nih.gov/pubmed/17907805
http://dx.doi.org/10.1371/journal.ppat.0030139