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Stimulus Design for Model Selection and Validation in Cell Signaling

Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. One challenge in model development is that, with limited experimental data...

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Detalles Bibliográficos
Autores principales: Apgar, Joshua F, Toettcher, Jared E, Endy, Drew, White, Forest M, Tidor, Bruce
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323406/
https://www.ncbi.nlm.nih.gov/pubmed/18282085
http://dx.doi.org/10.1371/journal.pcbi.0040030