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Relief of Preintegration Inhibition and Characterization of Additional Blocks for HIV Replication in Primary Mouse T Cells

Development of a small animal model to study HIV replication and pathogenesis has been hampered by the failure of the virus to replicate in non-primate cells. Most studies aimed at achieving replication in murine cells have been limited to fibroblast cell lines, but generating an appropriate model r...

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Detalles Bibliográficos
Autores principales: Zhang, Jing-xin, Diehl, Gretchen E., Littman, Dan R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323578/
https://www.ncbi.nlm.nih.gov/pubmed/18446227
http://dx.doi.org/10.1371/journal.pone.0002035