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Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling

DNA hypermethylation is a common epigenetic abnormality in cancer and may serve as a useful marker to clone cancer-related genes as well as a marker of clinical disease activity. To identify CpG islands methylated in prostate cancer, we used methylated CpG island amplification (MCA) coupled with rep...

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Detalles Bibliográficos
Autores principales: Chung, Woonbok, Kwabi-Addo, Bernard, Ittmann, Michael, Jelinek, Jaroslav, Shen, Lanlan, Yu, Yinhua, Issa, Jean-Pierre J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323612/
https://www.ncbi.nlm.nih.gov/pubmed/18446232
http://dx.doi.org/10.1371/journal.pone.0002079