Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells

BACKGROUND: Statins are shown to have cholesterol-independent properties such as anti-inflammation and immunomodulation. Activated hepatic stellate cells (HSCs) acquire the capacity to synthesize matrix proteins in damaged liver. We tested the hypothesis that atorvastatin may be capable of inducing...

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Detalles Bibliográficos
Autores principales: Aprigliano, Isabella, Dudas, Joszef, Ramadori, Giuliano, Saile, Bernhard
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Basic Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324535/
https://www.ncbi.nlm.nih.gov/pubmed/18339080
http://dx.doi.org/10.1111/j.1478-3231.2008.01682.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324535/
https://www.ncbi.nlm.nih.gov/pubmed/18339080
http://dx.doi.org/10.1111/j.1478-3231.2008.01682.x

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