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Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells
BACKGROUND: Statins are shown to have cholesterol-independent properties such as anti-inflammation and immunomodulation. Activated hepatic stellate cells (HSCs) acquire the capacity to synthesize matrix proteins in damaged liver. We tested the hypothesis that atorvastatin may be capable of inducing...
Autores principales: | Aprigliano, Isabella, Dudas, Joszef, Ramadori, Giuliano, Saile, Bernhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324535/ https://www.ncbi.nlm.nih.gov/pubmed/18339080 http://dx.doi.org/10.1111/j.1478-3231.2008.01682.x |
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