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Prognostic significance of DNA repair proteins MLH1, MSH2 and MGMT expression in non-small-cell lung cancer and precursor lesions

AIMS: To investigate the role of DNA repair proteins and their prognostic significance in non-small-cell lung cancer (NSCLC). METHODS AND RESULTS: A retrospective analysis of 108 cases of stage I–II NSCLC was undertaken. Immunohistochemical expression of DNA repair proteins MLH1, MSH2 and MGMT was a...

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Detalles Bibliográficos
Autores principales: Cooper, W A, Kohonen-Corish, M R J, Chan, C, Kwun, S Y, McCaughan, B, Kennedy, C, Sutherland, R L, Lee, C-S
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2325921/
https://www.ncbi.nlm.nih.gov/pubmed/18370958
http://dx.doi.org/10.1111/j.1365-2559.2008.02999.x