Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healing

AIMS: Matrix metalloproteinases (MMPs) play a major role in wound healing: they can degrade all components of the extracellular matrix. In diabetic foot ulcers there is an excess of MMPs and a decrease of the tissue inhibitors of MMPs (TIMPs). This imbalance is probably one cause of impaired healing...

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Detalles Bibliográficos
Autores principales: Muller, M, Trocme, C, Lardy, B, Morel, F, Halimi, S, Benhamou, P Y
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2326726/
https://www.ncbi.nlm.nih.gov/pubmed/18387077
http://dx.doi.org/10.1111/j.1464-5491.2008.02414.x