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Evidence that high von Willebrand factor and low ADAMTS-13 levels independently increase the risk of a non-fatal heart attack

Background: A disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13) may influence von Willebrand factor (VWF) levels and consequently the risk of myocardial infarction (MI). Moreover, ADAMTS-13 influences hemostatic plug formation in mouse models. We therefore s...

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Detalles Bibliográficos
Autores principales: CRAWLEY, J T B, LANE, D A, WOODWARD, M, RUMLEY, A, LOWE, G D O
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2327206/
https://www.ncbi.nlm.nih.gov/pubmed/18194418
http://dx.doi.org/10.1111/j.1538-7836.2008.02902.x