Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

Cells respond to DNA double-strand breaks (DSBs) and uncapped telomeres by recruiting checkpoint and repair factors to the site of lesions. Single-stranded DNA (ssDNA) is an important intermediate in the repair of DSBs and is produced also at uncapped telomeres. Here, we provide evidence that bindin...

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Detalles Bibliográficos
Autores principales: Lazzaro, Federico, Sapountzi, Vasileia, Granata, Magda, Pellicioli, Achille, Vaze, Moreshwar, Haber, James E, Plevani, Paolo, Lydall, David, Muzi-Falconi, Marco
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2328446/
https://www.ncbi.nlm.nih.gov/pubmed/18418382
http://dx.doi.org/10.1038/emboj.2008.81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2328446/
https://www.ncbi.nlm.nih.gov/pubmed/18418382
http://dx.doi.org/10.1038/emboj.2008.81

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