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R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation
BACKGROUND: Up to now, two loci have been involved in XX sex-reversal in mammals following loss-of-function mutations, PIS (Polled Intersex Syndrome) in goats and R-spondin1 (RSPO1) in humans. Here, we analyze the possible interaction between these two factors during goat gonad development. Furtherm...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329615/ https://www.ncbi.nlm.nih.gov/pubmed/18384673 http://dx.doi.org/10.1186/1471-213X-8-36 |