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The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation
BACKGROUND: The majority of our bones develop through the process of endochondral ossification that involves chondrocyte proliferation and hypertrophic differentiation in the cartilage growth plate. A large number of growth factors and hormones have been implicated in the regulation of growth plate...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329617/ https://www.ncbi.nlm.nih.gov/pubmed/18405384 http://dx.doi.org/10.1186/1471-213X-8-40 |