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The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation

BACKGROUND: The majority of our bones develop through the process of endochondral ossification that involves chondrocyte proliferation and hypertrophic differentiation in the cartilage growth plate. A large number of growth factors and hormones have been implicated in the regulation of growth plate...

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Detalles Bibliográficos
Autores principales: Ulici, Veronica, Hoenselaar, Katie D, Gillespie, J Ryan, Beier, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329617/
https://www.ncbi.nlm.nih.gov/pubmed/18405384
http://dx.doi.org/10.1186/1471-213X-8-40