Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

BACKGROUND: The TP53 polymorphisms Arg72Pro (Ex4+199 G>C) and Ins16 (IVS3+24 ins16) have been proposed to modify risk of breast cancer associated with germline BRCA1 and BRCA2 mutations. Allele frequencies of these polymorphisms were investigated to determine if they modify risk in BRCA mutation...

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Detalles Bibliográficos
Autores principales: Cavallone, Luca, Arcand, Suzanna L, Maugard, Christine, Ghadirian, Parviz, Mes-Masson, Anne-Marie, Provencher, Diane, Tonin, Patricia N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329651/
https://www.ncbi.nlm.nih.gov/pubmed/18402691
http://dx.doi.org/10.1186/1471-2407-8-96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329651/
https://www.ncbi.nlm.nih.gov/pubmed/18402691
http://dx.doi.org/10.1186/1471-2407-8-96

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