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Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line

BACKGROUND: Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum erythrocyte membrane protein 1 family member, termed VAR2CSA. VAR2CSA appears to be the main ligand responsi...

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Detalles Bibliográficos
Autores principales: Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329659/
https://www.ncbi.nlm.nih.gov/pubmed/18364051
http://dx.doi.org/10.1186/1475-2875-7-51