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Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line
BACKGROUND: Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum erythrocyte membrane protein 1 family member, termed VAR2CSA. VAR2CSA appears to be the main ligand responsi...
Autores principales: | Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329659/ https://www.ncbi.nlm.nih.gov/pubmed/18364051 http://dx.doi.org/10.1186/1475-2875-7-51 |
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