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Slp1 and Slp2-a Localize to the Plasma Membrane of CTL and Contribute to Secretion from the Immunological Synapse

Rab27a is required for polarized secretion of lysosomes from cytotoxic T lymphocytes (CTLs) at the immunological synapse. A series of Rab27a-interacting proteins have been identified; however, only Munc13-4 has been found to be expressed in CTL. In this study, we screened for expression of the synap...

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Detalles Bibliográficos
Autores principales: Holt, Oliver, Kanno, Eiko, Bossi, Giovanna, Booth, Sarah, Daniele, Tiziana, Santoro, Alessandra, Arico, Maurizio, Saegusa, Chika, Fukuda, Mitsunori, Griffiths, Gillian M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329822/
https://www.ncbi.nlm.nih.gov/pubmed/18266782
http://dx.doi.org/10.1111/j.1600-0854.2008.00714.x