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Slp1 and Slp2-a Localize to the Plasma Membrane of CTL and Contribute to Secretion from the Immunological Synapse
Rab27a is required for polarized secretion of lysosomes from cytotoxic T lymphocytes (CTLs) at the immunological synapse. A series of Rab27a-interacting proteins have been identified; however, only Munc13-4 has been found to be expressed in CTL. In this study, we screened for expression of the synap...
Autores principales: | Holt, Oliver, Kanno, Eiko, Bossi, Giovanna, Booth, Sarah, Daniele, Tiziana, Santoro, Alessandra, Arico, Maurizio, Saegusa, Chika, Fukuda, Mitsunori, Griffiths, Gillian M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329822/ https://www.ncbi.nlm.nih.gov/pubmed/18266782 http://dx.doi.org/10.1111/j.1600-0854.2008.00714.x |
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