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The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

Macroautophagy, a constitutive process in higher eukaryotic cells, mediates degradation of many long-lived proteins and organelles. The actual events occurring during the process in the dynamic system of a living cell have never been thoroughly investigated. We aimed to develop a live-cell assay in...

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Detalles Bibliográficos
Autores principales: Jahreiss, Luca, Menzies, Fiona M, Rubinsztein, David C
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329914/
https://www.ncbi.nlm.nih.gov/pubmed/18182013
http://dx.doi.org/10.1111/j.1600-0854.2008.00701.x