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GM-CSF/IL-3/IL-5 receptor common β chain (CD131) expression as a biomarker of antigen-stimulated CD8(+ )T cells

BACKGROUND: Upon Ag-activation cytotoxic T cells (CTLs) produce IFN-γ GM-CSF and TNF-α, which deliver simultaneously pro-apoptotic and pro-inflammatory signals to the surrounding microenvironment. Whether this secretion affects in an autocrine loop the CTLs themselves is unknown. METHODS: Here, we c...

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Detalles Bibliográficos
Autores principales: Selleri, Silvia, Deola, Sara, Pos, Zoltan, Jin, Ping, Worschech, Andrea, Slezak, Stefanie L, Rumio, Cristiano, Panelli, Monica C, Maric, Dragan, Stroncek, David F, Wang, Ena, Marincola, Francesco M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330025/
https://www.ncbi.nlm.nih.gov/pubmed/18412971
http://dx.doi.org/10.1186/1479-5876-6-17