Promoter-Wide Hypermethylation of the Ribosomal RNA Gene Promoter in the Suicide Brain

BACKGROUND: Alterations in gene expression in the suicide brain have been reported and for several genes DNA methylation as an epigenetic regulator is thought to play a role. rRNA genes, that encode ribosomal RNA, are the backbone of the protein synthesis machinery and levels of rRNA gene promoter m...

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Detalles Bibliográficos
Autores principales: McGowan, Patrick O., Sasaki, Aya, Huang, Tony C. T., Unterberger, Alexander, Suderman, Matthew, Ernst, Carl, Meaney, Michael J., Turecki, Gustavo, Szyf, Moshe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330072/
https://www.ncbi.nlm.nih.gov/pubmed/18461137
http://dx.doi.org/10.1371/journal.pone.0002085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330072/
https://www.ncbi.nlm.nih.gov/pubmed/18461137
http://dx.doi.org/10.1371/journal.pone.0002085

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