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Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance

microRNAs (miRNAs) are small non-coding RNAs that regulate mRNA stability and translation through the action of the RNAi-induced silencing complex (RISC). Our current understanding of miRNA function is inferred largely from studies of the effects of miRNAs on steady-state mRNA levels and from seed m...

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Detalles Bibliográficos
Autores principales: Hendrickson, David G., Hogan, Daniel J., Herschlag, Daniel, Ferrell, James E., Brown, Patrick O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330160/
https://www.ncbi.nlm.nih.gov/pubmed/18461144
http://dx.doi.org/10.1371/journal.pone.0002126