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A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity
The c-myb promoter contains multiple GGA repeats beginning 17 bp downstream of the transcription initiation site. GGA repeats have been previously shown to form unusual DNA structures in solution. Results from chemical footprinting, circular dichroism and RNA and DNA polymerase arrest assays on olig...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330228/ https://www.ncbi.nlm.nih.gov/pubmed/18252774 http://dx.doi.org/10.1093/nar/gkm1069 |