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A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity

The c-myb promoter contains multiple GGA repeats beginning 17 bp downstream of the transcription initiation site. GGA repeats have been previously shown to form unusual DNA structures in solution. Results from chemical footprinting, circular dichroism and RNA and DNA polymerase arrest assays on olig...

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Detalles Bibliográficos
Autores principales: Palumbo, SunMi L., Memmott, Regan M., Uribe, Diana J., Krotova-Khan, Yulia, Hurley, Laurence H., Ebbinghaus, Scot W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330228/
https://www.ncbi.nlm.nih.gov/pubmed/18252774
http://dx.doi.org/10.1093/nar/gkm1069