C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity

The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA-binding domain is highly conserved among the three family members p53, p63 and p73, the C-terminal domains (CTDs) are diverse and subject to alternative splicing...

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Detalles Bibliográficos
Autores principales: Sauer, Markus, Bretz, Anne Catherine, Beinoraviciute-Kellner, Rasa, Beitzinger, Michaela, Burek, Christof, Rosenwald, Andreas, Harms, Gregory S., Stiewe, Thorsten
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330244/
https://www.ncbi.nlm.nih.gov/pubmed/18267967
http://dx.doi.org/10.1093/nar/gkn044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330244/
https://www.ncbi.nlm.nih.gov/pubmed/18267967
http://dx.doi.org/10.1093/nar/gkn044

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