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C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity
The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA-binding domain is highly conserved among the three family members p53, p63 and p73, the C-terminal domains (CTDs) are diverse and subject to alternative splicing...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330244/ https://www.ncbi.nlm.nih.gov/pubmed/18267967 http://dx.doi.org/10.1093/nar/gkn044 |