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The effect of sequence context on spontaneous Polζ-dependent mutagenesis in Saccharomyces cerevisiae
The Polζ translesion synthesis (TLS) DNA polymerase is responsible for over 50% of spontaneous mutagenesis and virtually all damage-induced mutagenesis in yeast. We previously demonstrated that reversion of the lys2ΔA746 −1 frameshift allele detects a novel type of +1 frameshift that is accompanied...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2330250/ https://www.ncbi.nlm.nih.gov/pubmed/18276637 http://dx.doi.org/10.1093/nar/gkn054 |