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Molecular cloning, expression, purification and crystallographic analysis of PRRSV 3CL protease
3CL protease, a viral chymotrypsin-like proteolytic enzyme, plays a pivotal role in the transcription and replication machinery of many RNA viruses, including porcine reproductive and respiratory syndrome virus (PRRSV). In this study, the full-length 3CL protease from PRRSV was cloned and overexpres...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335157/ https://www.ncbi.nlm.nih.gov/pubmed/17671377 http://dx.doi.org/10.1107/S1744309107033234 |