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Polymorphism Interaction Analysis (PIA): a method for investigating complex gene-gene interactions

BACKGROUND: The risk of common diseases is likely determined by the complex interplay between environmental and genetic factors, including single nucleotide polymorphisms (SNPs). Traditional methods of data analysis are poorly suited for detecting complex interactions due to sparseness of data in hi...

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Detalles Bibliográficos
Autores principales: Mechanic, Leah E, Luke, Brian T, Goodman, Julie E, Chanock, Stephen J, Harris, Curtis C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335300/
https://www.ncbi.nlm.nih.gov/pubmed/18325117
http://dx.doi.org/10.1186/1471-2105-9-146