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Polymorphism Interaction Analysis (PIA): a method for investigating complex gene-gene interactions
BACKGROUND: The risk of common diseases is likely determined by the complex interplay between environmental and genetic factors, including single nucleotide polymorphisms (SNPs). Traditional methods of data analysis are poorly suited for detecting complex interactions due to sparseness of data in hi...
Autores principales: | Mechanic, Leah E, Luke, Brian T, Goodman, Julie E, Chanock, Stephen J, Harris, Curtis C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335300/ https://www.ncbi.nlm.nih.gov/pubmed/18325117 http://dx.doi.org/10.1186/1471-2105-9-146 |
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