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Using quality scores and longer reads improves accuracy of Solexa read mapping

BACKGROUND: Second-generation sequencing has the potential to revolutionize genomics and impact all areas of biomedical science. New technologies will make re-sequencing widely available for such applications as identifying genome variations or interrogating the oligonucleotide content of a large sa...

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Detalles Bibliográficos
Autores principales: Smith, Andrew D, Xuan, Zhenyu, Zhang, Michael Q
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335322/
https://www.ncbi.nlm.nih.gov/pubmed/18307793
http://dx.doi.org/10.1186/1471-2105-9-128