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Polymorphisms in the PTPN22 region are associated with psoriasis of early onset

BACKGROUND: Psoriasis, a chronic inflammatory skin disease, affects approximately 2% of the population worldwide. Although the aetiology of psoriasis is poorly understood, patients with disease of early onset (Type I, age of onset ≤ 40 years) usually have a strong genetic component to the disease. O...

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Detalles Bibliográficos
Autores principales: Smith, RhLl, Warren, RB, Eyre, S, Ke, X, Young, HS, Allen, M, Strachan, D, McArdle, W, Gittins, MP, Barker, JNWN, Griffiths, CEM, Worthington, J
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2342636/
https://www.ncbi.nlm.nih.gov/pubmed/18341666
http://dx.doi.org/10.1111/j.1365-2133.2008.08482.x