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Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia

The hydroxycarbamide (HC)-inducible small guanosine triphosphate (GTP)-binding protein, secretion-associated and RAS-related (SAR) protein has recently been shown to play a pivotal role in HBG induction and erythroid maturation by causing cell apoptosis and G1/S-phase arrest. Our preliminary analysi...

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Detalles Bibliográficos
Autores principales: Kumkhaek, Chutima, Taylor, James G, Zhu, Jianqiong, Hoppe, Carolyn, Kato, Gregory J, Rodgers, Griffin P
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2344124/
https://www.ncbi.nlm.nih.gov/pubmed/18318767
http://dx.doi.org/10.1111/j.1365-2141.2008.07045.x