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Mast Cell-Derived Histamine Mediates Cystitis Pain

BACKGROUND: Mast cells trigger inflammation that is associated with local pain, but the mechanisms mediating pain are unclear. Interstitial cystitis (IC) is a bladder disease that causes debilitating pelvic pain of unknown origin and without consistent inflammation, but IC symptoms correlate with el...

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Detalles Bibliográficos
Autores principales: Rudick, Charles N., Bryce, Paul J., Guichelaar, Laura A., Berry, Ruth E., Klumpp, David J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346452/
https://www.ncbi.nlm.nih.gov/pubmed/18461160
http://dx.doi.org/10.1371/journal.pone.0002096