An Inducible and Reversible Mouse Genetic Rescue System

Inducible and reversible regulation of gene expression is a powerful approach for uncovering gene function. We have established a general method to efficiently produce reversible and inducible gene knockout and rescue in mice. In this system, which we named iKO, the target gene can be turned on and...

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Detalles Bibliográficos
Autores principales: Zeng, Hongkui, Horie, Kyoji, Madisen, Linda, Pavlova, Maria N., Gragerova, Galina, Rohde, Alex D., Schimpf, Brian A., Liang, Yuqiong, Ojala, Ethan, Kramer, Farah, Roth, Patricia, Slobodskaya, Olga, Dolka, Io, Southon, Eileen A., Tessarollo, Lino, Bornfeldt, Karin E., Gragerov, Alexander, Pavlakis, George N., Gaitanaris, George A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346557/
https://www.ncbi.nlm.nih.gov/pubmed/18464897
http://dx.doi.org/10.1371/journal.pgen.1000069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346557/
https://www.ncbi.nlm.nih.gov/pubmed/18464897
http://dx.doi.org/10.1371/journal.pgen.1000069

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