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Evidence for a functional dimeric form of the PcrA helicase in DNA unwinding

PcrA helicase, a member of the superfamily 1, is an essential enzyme in many bacteria. The first crystal structures of helicases were obtained with PcrA. Based on structural and biochemical studies, it was proposed and then generally believed that PcrA is a monomeric helicase that unwinds DNA by an...

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Detalles Bibliográficos
Autores principales: Yang, Ye, Dou, Shuo-Xing, Ren, Hua, Wang, Peng-Ye, Zhang, Xing-Dong, Qian, Min, Pan, Bing-Yi, Xi, Xu Guang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346599/
https://www.ncbi.nlm.nih.gov/pubmed/18276648
http://dx.doi.org/10.1093/nar/gkm1174