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Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase
Our previous publication shows that Sulfolobus solfataricus Dpo4 utilizes an ‘induced-fit’ mechanism to select correct incoming nucleotides at 37°C. Here, we provide a comprehensive report elucidating the kinetic mechanism of a DNA polymerase at a reaction temperature higher than 37°C in an attempt...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346602/ https://www.ncbi.nlm.nih.gov/pubmed/18276639 http://dx.doi.org/10.1093/nar/gkn004 |