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Empirical Bayes models for multiple probe type microarrays at the probe level

BACKGROUND: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are adjusted towards a global estimate, producing more stable results compared to ordinary t-tests. However, for Affymetrix...

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Detalles Bibliográficos
Autores principales: Åstrand, Magnus, Mostad, Petter, Rudemo, Mats
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2358895/
https://www.ncbi.nlm.nih.gov/pubmed/18366694
http://dx.doi.org/10.1186/1471-2105-9-156