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Empirical Bayes models for multiple probe type microarrays at the probe level
BACKGROUND: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are adjusted towards a global estimate, producing more stable results compared to ordinary t-tests. However, for Affymetrix...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2358895/ https://www.ncbi.nlm.nih.gov/pubmed/18366694 http://dx.doi.org/10.1186/1471-2105-9-156 |