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Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo

Senescence is a distinct cellular response induced by DNA-damaging agents and other sublethal stressors and may provide novel benefits in cancer therapy. However, in an ageing model, senescent fibroblasts were found to stimulate the proliferation of cocultured cells. To address whether senescence in...

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Detalles Bibliográficos
Autores principales: Ewald, J A, Desotelle, J A, Almassi, N, Jarrard, D F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2359629/
https://www.ncbi.nlm.nih.gov/pubmed/18349844
http://dx.doi.org/10.1038/sj.bjc.6604288